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Ubiquitin Isopeptidase-IN-G5
CAS No. 108477-18-5
Ubiquitin Isopeptidase-IN-G5( NSC-144303 | NSC 144303 | NSC144303 )
Catalog No. M10333 CAS No. 108477-18-5
A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 82 | Get Quote |
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| 10MG | 141 | Get Quote |
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| 25MG | 306 | Get Quote |
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| 50MG | 541 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameUbiquitin Isopeptidase-IN-G5
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
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DescriptionA small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases; induce a unique apoptotic pathway, which includes a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa, stabilization of the IAP antagonist Smac, but also the involvement of the death receptor pathway.
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In Vitro——
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In Vivo——
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SynonymsNSC-144303 | NSC 144303 | NSC144303
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PathwayProteasome/Ubiquitin
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TargetDUB
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RecptorDUB
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Research Area——
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Indication——
Chemical Information
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CAS Number108477-18-5
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Formula Weight414.3887
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Molecular FormulaC19H14N2O7S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 31 mg/mL
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SMILESO=C(/C(C1)=C/C2=CC=C([N+]([O-])=O)C=C2)/C(CS1(=O)=O)=C/C3=CC=C([N+]([O-])=O)C=C3
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Chemical Name4H-Thiopyran-4-one, tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-, 1,1-dioxide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Aleo E, et al. Cancer Res. 2006 Sep 15;66(18):9235-44.
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